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Doxycycline is an antibiotic that has been in use since the 1960s. It is also known as Vibramycin-D, Efracea, and Periostat. Doxycycline is a 'bacteriostatic' that inhibits the growth of bacteria but doesn't kill them directly. Amoxicillin (an antibiotic you may be more familiar with) is 'bactericidal' that directly kills the bacteria. It is available on the NHS to treat a wide range of bacterial infections such as chest infections and rosacea (skin condition).

Following promising trials in the USA and France, Doxycycline (or DoxyPEP)  is also being touted as a preventative measure against STIs - a "morning-after pill" to prevent chlamydia, gonorrhoea and syphilis. However, is not yet approved for use in the UK and it's unclear if/ when this will change anytime soon. Antibiotic resistance is a serious concern, the benefits being outweighed by the potential for antibiotic resistance to develop in STIs and other bacteria.

Doxycycline | NHS
Doxycycline | Wikipedia
Doxycycline | National Institute for Health and Care Excellence (NICE)
Using antibiotics to prevent STIs | nam aidsmap
DoxyPEP: the future of STI prevention? | Love Tank

The morning-after pill for STIs”: everything you need to know | The Face | 22 Jan 2024
Doxycycline PEP significantly reduces STIs in people at high risk of infections | i-base | 3 Aug 2022
An old drug offers a new way to stop STIs | NPR | 11 Jul 2023
BASHH updated position statement on doxycycline as prophylaxis for sexually transmitted infections | BMJ | M Kohli, N Medland, H Fifer, J Saunders | May 1, 2022

CDC to recommend antibiotic after sex for some to prevent STIs | CBS News | 4 Oct 2023 | 3m 51s
AIDS 2022: Antibiotics to prevent STIs | aidsmap | 1 Aug 2022 | 2m 13s

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